Type 2 diabetes mellitus has reached an epidemic level with more than 12 percent of Americans diagnosed with diabetes with an additional 38 percent having prediabetes (most of these patients are currently not diagnosed). The disease is usually diagnosed by an elevated HemoglobinA1C level which measures the average blood sugar level in the previous 90 days of more than 6.5%.

To better understand type 2 diabetes, we have to look at pathophysiology of the disease. In other words, what causes type 2 diabetes. Elevated blood glucose level is not the disease but it is just one of its symptoms. The main cause of type 2 diabetes is insulin resistance which means the body cells become resistant to the effect the insulin. One of the main function of the insulin is to push the blood glucose into the cell. When the cells become resistance to insulin, the glucose is not able to enter inside the cells to be used and it remains elevated in the blood stream.

The body attempts to overcome the insulin resistance by making the pancreas secrete more insulin causing hyperinsulinemia elevated insulin level in the blood.

The hyperinsulinemia initially is able to overcome the insulin resistance in an attempt to keep the blood sugar under control but the chronically elevated insulin levels cause the insulin receptor to be less sensitive making the insulin resistance even worse which leads to even higher insulin levels and so on.

The high insulin level and insulin resistance are responsible for many of the complications of type 2 diabetes mellitus. The most dangerous complications for diabetes such as heart attack and stroke are mainly due to insulin resistance and not high blood glucose level and the patient will develop these complications even if blood glucose levels are controlled with either oral medications or with insulin injections. That is why in many different studies, it was shown that there is no added health benefits to keep the blood sugar under a very strict control with medication and some studies actually showed increases in mortality and morbidity with aggressive treatment to keep the blood sugar low compared with the less intense treatment regimens.1

What happens when we treat the patient with type 2 diabetes with insulin injections? Most of the patients treated with the oral medications fail to respond to this after several years. They are subsequently started on insulin in an effort to lower the blood sugar. As we have seen earlier, these patients already have elevated blood insulin levels and injecting them with more insulin only serves to increase their insulin level even higher and make their insulin resistance much worse. Insulin is also the hormone that drives obesity by promoting fat synthesis and inhibiting fat loss. Most of these patients gain a significant amount of fat after starting them on insulin therapy. While insulin injections are a lifesaving treatment in patient with type 1 diabetes, its role in the treatment in type 2 diabetes is questionable.

The Diabetes Reversal Program offered by The Metabolism Clinic has a completely different approach. It is a comprehensive program that treats the root causes of type 2 diabetes.


The Metabolism Clinic is established as the destination for weight loss and reversal of diabetes. Based in Charlotte, North Carolina. www.themetabolismclinic.com